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Inhibitex initiates INX-189 combination Phase 2 trial in HCV-infected genotype 2/3 patients

August 06, 2017

Among the 30 patients, all of whom were treated with SPI-1620 and docetaxel, 5 partial responses (PR) were seen. Of the 5 partial responses, two were in prostate cancer, and those patients experienced a prolonged duration of response of approximately 12 and 18 months. Encouraging antitumor activity was also seen in patients with cholangiocarcinoma, transitional cell urothelial carcinoma, and ovarian cancer.

"We are very pleased with the promising top-line data from the SPI-1620 study and believe that it could be an effective drug in the treatment of solid tumors," said Rajesh C. Shrotriya, MD, Chairman, Chief Executive Officer, and President of Spectrum Pharmaceuticals. "Spectrum is committed to bringing safe and effective treatment options to cancer patients. We look forward to continuing the development of SPI-1620, and we currently expect to initiate a Phase 2 study for SPI-1620 in 2012."

Source: Spectrum Pharmaceuticals