Kinexus launches TranscriptoNET KnowledgeBase for human gene expression study

July 18, 2017

TranscriptoNET is a powerful tool for discovery of genes that are uniquely or commonly expressed throughout the human body, and can be used to uncover possible functional interactions amongst the 23,000 proteins encoded by the human genome based on their co-expression patterns. In the selection of human specimens for inclusion in TranscriptoNET, special emphasis was placed on human tumours and cancer cell lines to identify the differential regulation of genes in cancer. TranscriptoNET can be used to uncover new potential oncogenes and tumour suppressor genes that may encode cancer protein biomarkers and drug targets.

"While all human cells carry the same genes, the production of proteins from these genes is markedly different and dynamically changing in the various cell types found in the tissues and organs of the body" commented Dr. Steven Pelech, President and Chief Scientific Officer of Kinexus and a professor in the Department of Medicine at the University of British Columbia. "While gene microarray data has been available for nearly a decade from the NCBI GEO database, TranscriptoNET now enables researchers to compare the results from thousands of human specimens directly with each other and conduct meta-analyses."

SOURCE Kinexus Bioinformatics Corporation