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UH Rainbow physicians to participate in two new clinical trials with AsthmaNet

June 19, 2017

The purpose of this study is to learn if taking Vitamin D in addition to an inhaled steroid -- the most effective treatment for asthma available today -- will help prevent worsening asthma symptoms and asthma exacerbations in people who have low Vitamin D levels, estimated to be up to 30 percent of the population.

"Patients who live in urban areas, especially in the northern part of the United States, such as Ohio, tend to be deficient in Vitamin D. We also see higher rates of asthma in urban centers such as Cleveland," said Dr. Ross. "Patients who have low levels of Vitamin D tend to have more severe and harder to control asthma. One reason might be that having low levels of vitamin D make it harder for inhaled steroids to work well. Although we think of vitamin D as an important vitamin for healthy bones, there is increasing evidence that it is also important in the immune system and fighting inflammation."

"Despite how common asthma is, it remains poorly understood and, in many cases, poorly treated," said James Chmiel, M.D., principal investigator for the AsthmaNet site at UH Rainbow and associate professor of pediatrics at Case Western Reserve University School of Medicine. "The possibility that improving treatment may be as easy as taking a vitamin which is activated in the skin by normal exposure to sunlight is exciting."

Source: University Hospitals Case Medical Center