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Isosorbide Mononitrate General Information

Isosorbide Mononitrate is used to prevent chest pain which is a symptom of angina and other heart conditions including heart failure.

Isosorbide Mononitrate can be used to decrease the frequency and severity of anginal (chest pain) episodes and to reduce the need for sublingual (taken under the tongue) nitroglycerin.

Isosorbide Mononitrate widens the arteries that carry blood to the heart muscle and relax the veins that return blood from the body to the heart. Together these actions allow more oxygen to reach the heart muscle and reduce the work of the heart. This lowers the overall strain on the heart reducing the risk of angina and relieving the pain associated with an acute angina attack.

Isosorbide Mononitrate Recommendations

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Isosorbide Mononitrate exactly as directed.

Isosorbide Mononitrate is usually taken first thing in the morning before breakfast. Take each dose with a full glass of water.

Swallow the extended-release forms of Isosorbide Mononitrate whole. Do not crush or chew them. They are specially formulated to release medication slowly into your body.

Do not stop taking Isosorbide Mononitrate suddenly.

It is best not to drink alcohol while you are taking Isosorbide Mononitrate. If you do drink alcohol, drink only a little and be aware of its effect on you.

If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up.


Isosorbide Mononitrate Storage

Store medication in a cool dry place between 36 and 86 degrees F (2 to 30 degrees C) in a tight container.
Do not store in the bathroom.


Isosorbide Mononitrate Possible Side Effects

Headache, dizziness, flushing, rapid heartbeat or restlessness may occur as your body adjusts to the medication.
If they persist or become bothersome, inform your doctor.
To prevent dizziness and lightheadedness when rising from a seated or lying position, get up slowly.
Notify your doctor if you experience: blurred vision, dry mouth, skin rash, nausea.
Headache is often a sign the medication is working.
Treat headaches with an aspirin or non-aspirin pain reliever as recommended by your doctor.
If the headaches continue or become severe, notify your doctor.
If you notice other effects not listed above, contact your doctor or pharmacist.


Isosorbide Mononitrate Precautions

Tell your doctor if you have ever had: angle-closure glaucoma, blood disorders, low blood pressure, recent head injury, recent heart attack, any allergies (especially to nitrates).
Caution is advised when using Isosorbide Mononitrate in the elderly because they may be more sensitive to the effects of Isosorbide Mononitrate, especially the blood pressure lowering effects.
Isosorbide Mononitrate should be used only if clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.
Since small amounts of Isosorbide Mononitrate are found in breast milk, consult your doctor before breast-feeding.
To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly.
Also limit your intake of alcoholic beverages and avoid overheating which will aggravate these effects.


Isosorbide Mononitrate Missed Dose

If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule.
Do not double-up the dose to catch up.


Isosorbide Mononitrate Interactions

Tell your doctor of any over-the-counter or prescription medication you may take especially: any medication for blood pressure, certain medications for migraines (ergot alkaloids), sildenafil, high doses of aspirin.
Do not start or stop any medicine without doctor or pharmacist approval.

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